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Registros recuperados: 30
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A simple mathematical model to determine the ideal empirical antibiotic therapy for bacteremic patients BJID
Tuon,Felipe F.; Rocha,Jaime L.; Leite,Talita M.; Dias,Camila.
BACKGROUND: Local epidemiological data are always helpful when choosing the best antibiotic regimen, but it is more complex than it seems as it may require the analysis of multiple combinations. The aim of this study was to demonstrate a simplified mathematical calculation to determine the most appropriate antibiotic combination in a scenario where monotherapy is doomed to failure. METHODS: The susceptibility pattern of 11 antibiotics from 216 positive blood cultures from January 2012 to January 2013 was analyzed based on local policy. The length of hospitalization before bacteremia and the unit (ward or intensive care unit) were the analyzed variables. Bacteremia was classified as early, intermediate or late. The antibiotics were combined according to the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mathematical model; Infection; Antibiotic; Bacteremia.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400360
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Aspectos clínicos e radiográficos da osteodistrofia hipertróica em cães: estudo retrospectivo de 16 casos Ciência Rural
Canola,Júlio Carlos; Andrade,Alexandre Lima de.
Descrevem-se 16 casos de osteodistrofia hipertrófica (OH) entre 13.483 casos levantados nos arquivos do Setor de radiologia do Hospital Veterinário "Governador Laudo Natel" da FCAVJ-UNESP, entre 1° de janeiro de 1977 a 31 de dezembro de 1995. A enfermidade mostrou-se de baixa manifestação clínica, atingindo cães jovens em fase de crescimento, pertencentes às raças de grande porte e supernutridos. Destaca-se ainda, a importância do exame radiográfico seriado no diagnóstico da enfermidade e principalmente como método de avaliação da reversão clínica do processo, mormente quando ocorre bacteremia associada.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Osteodistrofia hipertrófica; Bacteremia; Cão.
Ano: 1996 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781996000300014
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Assessing the diversity of the virulence potential ofEscherichia coli isolated from bacteremia in São Paulo, Brazil BJMBR
Santos,A.C.M.; Zidko,A.C.M.; Pignatari,A.C.; Silva,R.M..
Most of the knowledge of the virulence determinants of extraintestinal pathogenicEscherichia coli (ExPEC) comes from studies with human strains causing urinary tract infections and neonatal meningitis and animal strains causing avian colibacillosis. In this research, we analyzed the phylogenetic background, the presence of 20 ExPEC virulence factors, and the intrinsic virulence potential of 74 E. coli strains isolated in São Paulo, Brazil, from 74 hospitalized patients (43 males and 31 females) with unknown-source bacteremia. Unlike other places in the world, the bacteremic strains originated equally from phylogroups B2 (35%) and D (30%). A great variability in the profiles of virulence factors was noted in this survey. Nevertheless, 61% of the strains...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteremia; Extraintestinal pathogenic Escherichia coli; Virulence factors; Intrinsic virulence potential; Phylogenetic background.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100968
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Bacteremia due to Moraxella osloensis: a case report and literature review BJID
Maruyama,Yuta; Shigemura,Tomonari; Aoyama,Koki; Nagano,Noriyuki; Nakazawa,Yozo.
ABSTRACT Herein we report the case of a 10-year-old boy with an autosomal mosaic mutation who developed bacteremia. The causative agent was identified as Moraxella osloensis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene sequencing. In the pediatric population, there have been 13 case reports of infection attributed to M. osloensis and this is the fifth reported case of pediatric bacteremia due to M. osloensis. After Moraxella species infection was confirmed, the patient recovered with appropriate antimicrobial therapy. It is important to consider that M. osloensis can cause serious infections, such as bacteremia, in otherwise healthy children.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Moraxella osloensis; Bacteremia; MALDI-TOF MS; 16S rRNA gene sequencing.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000100060
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Bacteremic pneumococcal pneumonia: serotype distribution, antimicrobial susceptibility, severity scores, risk factors, and mortality in a single center in Chile BJID
Fica,Alberto; Bunster,Nicolás; Aliaga,Felipe; Olivares,Felipe; Porte,Lorena; Braun,Stephanie; Dabanch,Jeannette; Hormázabal,Juan Carlos; Hernández,Antonio; Benavides,María Guacolda.
AIMS:Bacteremic pneumococcal pneumonia (BPP) is a severe condition. To evaluate seasonal distribution, mortality, serotype frequencies, antimicrobial susceptibility, and different severity scores among patients with BPP.PATIENTS AND METHODS:Patients were identified by laboratory data and restricted to adulthood. Standard methods were used for serotyping and antimicrobial susceptibility. Risk factors were analyzed by univariate and multivariate methods. Severity scores (APACHE II, CURB-65 and CAP PIRO) were compared using ROC curves.RESULTS:Sixty events of community-acquired BPP occurred between 2005 and 2010. A seasonal pattern was detected. Mean age was 72.1 years old (81.4% >60 years). All had a predisposing factor. Previous influenza (3.3%) or...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus pneumoniae; Bacteremia; Serotyping; Microbial drug resistance; Risk factors; Mortality; Elderly; CURB-65; APACHE II; PIRO.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200115
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Brazilian experience in EU-CORE: daptomycin registry and treatment of serious Gram-positive infections BJID
Timerman,Artur; Brites,Carlos; Bicudo,Eliana; Grinbaum,Renato S.; Costa Filho,Rubens; Carrilho,Claudia D.M.; Bichels,Andre; Barreto,Tânia.
OBJECTIVES: To collect data about non-controlled prescribing use of daptomycin and its impact among Brazilian patients with serious Gram positive bacterial infection, as well as the efficacy and safety outcomes. MATERIALS AND METHODS: This is a multi-center, retrospective, non-interventional registry (August 01, 2009 to June 30, 2011) to collect data on 120 patients (44 patients in the first year and 76 patients in the second year) who had received at least one dose of commercial daptomycin in Brazil for the treatment of serious Gram-positive bacterial infection. RESULTS: Right-sided endocarditis (15.8%), complicated skin and soft tissue infections (cSSTI)wound (15.0%) and bacteremia-catheter-related (14.2%) were the most frequent primary infections; lung...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Daptomycin; Methicillin-resistant; Staphylococcus aureus; Bacteremia; Endocarditis; Skin diseases; Infectious.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600004
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Clinical and microbiological characteristics of bloodstream infections in a tertiary hospital in Maceió, Alagoas, Brazil BJID
Tenório,Maria Tereza Freitas; Porfírio,Zenaldo; Lopes,Antonio Carlos; Cendon,Sonia.
We observed the clinical and microbiological characteristics of several stages of bloodstream infections (BSI), as well as the mortality attributed to it in a tertiary hospital in the northeast of Brazil (in the city of Maceió, Alagoas). A prospective cohort of 143 patients who had at least one positive blood culture was enrolled in the study. Their clinical evolution was followed up for 30 days from October 2005 to December 2006. The relation among the qualitative variables was verified through Chi-square test. The significance level was 5%. The statistical package adopted was SPSS 15.0 for Windows. Up to the thirtieth day, 30.1% of the patients presented bacteremia and 69.9% developed sepsis.Among these, 20.3% developed severe sepsis and 10.5% septic...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bloodstream infections; Blood cultures; Bacteremia; Spesis.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000200011
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Clinical, epidemiological, and microbiological characteristics of bacteremia caused by high-level gentamicin-resistant Enterococcus faecalis BJMBR
Vigani,A.G.; Macedo de Oliveira,A.; Bratfich,O.J.; Stucchi,R.S.B.; Moretti,M.L..
Enterococcus spp bacteremia is associated with high mortality and the appearance of high-level gentamicin resistance (HLGR) created additional challenges for the treatment of these infections. We evaluated the epidemiological and clinical characteristics of patients with bacteremias caused by HLGR and non_HLGR Enterococcus faecalis isolates at a teaching hospital in the State of São Paulo, Brazil. Patients with bacteremia due to E. faecalis diagnosed between January 1999 and December 2003 were included in the study. We collected clinical, epidemiological, and microbiological data from medical records. Banked isolates were typed using pulsed-field gel electrophoresis. We identified 145 cases of E. faecalis bacteremia: 66 (45.5%) were caused by HLGR isolates...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Enterococcus faecalis; Bacteremia; High-level gentamicin resistance; Infection control; Enterococcus faecalis genotyping.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000010
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Evaluation of blood stream infections by Candida in three tertiary hospitals in Salvador, Brazil: a case-control study BJID
Barberino,Maria Goreth; Silva,Nanci; Rebouças,Carla; Barreiro,Katarine; Alcântara,Ana Paula; Netto,Eduardo M.; Albuquerque,Lígia; Brites,Carlos.
Invasive infections caused by Candida spp. are an important problem in immunocompromised patients. There is scarce data on the epidemiology of blood stream candidiasis in Salvador, Brazil. This study evaluates the risk factors associated with candidemia, among patients admitted to three tertiary, private hospitals, in Salvador, Brazil. We conducted a case-control, retrospective study to compare patients with diagnosis of candidemia in three different tertiary hospitals in Salvador, Brazil. Patients were matched for nosocomial, acquired infections, according to the causal agent: cases were defined by positive blood cultures for Candida species. Controls were those patients who had a diagnosis of systemic bacterial infection, with a positive blood culture to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Invasive candidiasis; Risk factors; Bacteremia.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000100008
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Fatal bacteremia due to Anaerobiospirillum succiniciproducens: first description in Brazil BJID
Secchi,Carina; Cantarelli,Vlademir Vicente; Pereira,Fabiana de Souza; Wolf,Hilda Helena Chaer; Brodt,Teresa Cristina Zenobini; Amaro,Maria Cristina O.; Inamine,Éverton.
Anaerobiospirillum succiniciproducens is an anaerobic, Gram-negative, spiral shaped bacteria, which is motile by means of bipolar tuffs of flagella. This organism appears to be a rare cause of bacteremia in humans, and it usually affects patients submitted to immunosuppressive therapy. Anaerobiospirillum succiniciproducens resembles Campylobacter spp. in Gram-stained preparations, however, it is considered resistant to most antimicrobial drugs that are used to treat Campylobacter infections. We observed Gram-negative, spiral shaped bacteria in Gram-stained preparations from blood culture flasks. Growth occurred only under anaerobic incubation, and identification to the species level was achieved by PCR amplification of the 16S rRNA gene, followed by direct...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Bacteremia; Anaerobiospirillum spp.; Anaerobiospirillum succiniciproducens.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000200008
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Fatal case of bacteremia caused by an atypical strain of Corynebacterium mucifaciens BJID
Cantarelli,Vlademir Vicente; Brodt,Teresa Cristina. Z.; Secchi,Carina; Inamine,Everton; Pereira,Fabiana de Souza; Pilger,Diogo Andre.
Corynebacterium species have often been considered normal skin flora or contaminants; however, in recent years they have been increasingly implicated in serious infections. Moreover, many new species have been discovered and old species renamed, especially after molecular biology techniques were introduced. Corynebacterium mucifaciens is mainly isolated from blood and from other normally-sterile body fluids; it forms slightly yellow, mucoid colonies on blood agar. We report a fatal case of bacteremia due to an atypical strain of C. mucifaciens. This strain had atypical colony morphology; analysis of the 16S rRNA gene was used to define the species.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Bacteremia; Blood infection; Corynebacterium; Corynebacterium mucifaciens.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600013
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Frequency of microorganisms isolated in patients with bacteremia in intensive care units in Colombia and their resistance profiles BJID
Cortes,Jorge Alberto; Leal,Aura Lucía; Montañez,Anita María; Buitrago,Giancarlo; Castillo,Juan Sebastián; Guzman,Lucy.
OBJECTIVE: The aim of this study was to describe the most frequently found bacterial microorganisms in bloodstream isolates taken from patients in intensive care units in Colombia and their resistance profiles. METHODS: This was a multicentre descriptive observational study that was carried out between January 2001 and June 2008 with laboratory data from 33 participating hospitals in a surveillance network. RESULTS: The most frequently found microorganisms were coagulase-negative Staphylococci 39.6%, Staphylococcus aureus 12.3%, Klebsiella pneumoniae 8.2%, Escherichia coli 5.7%, Acinetobacter baumannii, 4.0% and Pseudomonas aeruginosa 3.8%. Coagulase-negative Staphylococci registered greater than 70% oxacillin resistance rate. S. aureus presented a change...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteremia; Intensive care unit; Drug resistance; Anti-bacterial agents; Colombia/epidemiology; Epidemiologic surveillance.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300007
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Klebsiella ESBL bacteremia-mortality and risk factors BJID
Tuon,Felipe Francisco; Kruger,Margot; Terreri,Marcos; Penteado-Filho,Sergio R; Gortz,Lucas.
Background: Extended spectrum β-lactamase (ESBL)-producing bacteria have become recognized as a problem in South America. The aim of this study was to evaluate risk factors and mortality rate in bacteremia caused by ESBL-producing Klebsiella pneumoniae in a Brazilian hospital. Methods: A three-year retrospective cohort study with 104 cases of K. pneumoniae bacteremia (61 ESBL and 43 non-ESBL). Several clinical and laboratory variables were evaluated. The outcome of interest was 30-day mortality. The adequate treatment was evaluated according to antibiotic susceptibility. Results: Multivariable analysis showed that central venous catheter and mechanical ventilation were independent risk factors for ESBL. The duration of hospitalization before the bacteremia...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Klebsiella pneumoniae; Beta-lactamases; Bacteremia; Carbapenems.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000600016
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Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA BJID
Pereira,Eliezer Menezes; Schuenck,Ricardo Pinto; Nouér,Simone Aranha; Santos,Kátia Regina Netto dos.
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec type V were determined by PCR. Although treatment had been appropriated, the patient died after rapid progressive respiratory failure and another nosocomial sepsis. It is important not only to identify S. lugdunensis in view of its clinical course, but also to determine its susceptibility to oxacillin by detecting the mecA gene or its product.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Staphylococcus; Methicillin resistance; Bacteremia.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000300020
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Microbiology and clinical characteristics of viridans group streptococci in patients with cancer BJID
Guerrero-Del-Cueto,Fuensanta; Ibanes-Gutiérrez,Cyntia; Velázquez-Acosta,Consuelo; Cornejo-Juárez,Patricia; Vilar-Compte,Diana.
ABSTRACT This study assessed the microbiology, clinical syndromes, and outcomes of oncologic patients with viridans group streptococci isolated from blood cultures between January 1st, 2013 and December 31st, 2016 in a referral hospital in Mexico using the Bruker MALDI Biotyper. Antimicrobial sensitivity was determined using BD Phoenix 100 according to CLSI M100 standards. Clinical information was obtained from medical records and descriptive analysis was performed.Forty-three patients were included, 22 females and 21 males, aged 42 ± 17 years. Twenty (46.5%) patients had hematological cancer and 23 (53.5%) a solid malignancy. The viridans group streptococci isolated were Streptococcus mitis, 20 (46.5%); Streptococcus anginosus, 14 (32.6%); Streptococcus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Viridans group streptococci; Bacteremia; Bloodstream infection; Cancer; Mucosal damage.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000400323
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Ochrobactrum anthropi bacteremia in a preterm infant with cystic fibrosis BJM
Menezes,Fernando Gatti; Abreu,Maria Gabriela Ballalai; Kawagoe,Julia Yaeko; Warth,Arno Norberto; Deutsch,Alice D'Agostini; Dornaus,Maria Fernanda P S; Martino,Marines Dalla Valle; Correa,Luci.
Ochrobactrum anthropi infection in newborn patients is rare, and the treatment is challenging because of its widespread and unpredictable resistance to antimicrobial agents and discrepancies between in vitro susceptibility and in vivo efficacy. We report the clinical and microbiological characteristics of Ochrobactrum anthropi bacteremia in a preterm patient.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacteremia; Cystic fibrosis; Newborn; Meconium; Premature birth.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000200026
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Oxacilin-resistant Coagulase-negative staphylococci (CoNS) bacteremia in a general hospital at São Paulo city, Brasil BJM
D'Azevedo,P.A.; Secchi,C.; Antunes,A.L.S.; Sales,T.; Silva,F.M.; Tranchesi,R.; Pignatari,A.C.C..
In the last decades, coagulase-negative staphylococci (CoNS), especially Staphylococcus epidermidis have become an important cause of bloodstream infections. In addition, rates of methicillin-resistance among CoNS have increased substantially, leading to the use of glicopeptides for therapy. The objective of this study was to evaluate eleven consecutives clinically relevant cases of oxacillin-resistant CoNS bacteremia in a general hospital localized in São Paulo city, Brazil. Five different species were identified by different phenotypic methods, including S. epidermidis (5), S. haemolyticus (3), S. hominis (1), S. warneri (1) and S. cohnii subsp urealyticus (1). A variety of Pulsed Field Gel Electrophoresis profiles was observed by macrorestriction DNA...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coagulase-negative staphylococci; Bacteremia; Oxacillin; PFGE.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822008000400006
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Polyclonal outbreak of bacteremia caused by Burkholderia cepacia complex and the presumptive role of ultrasound gel BJID
Nannini,Esteban C.; Ponessa,Adriana; Muratori,Rosa; Marchiaro,Patricia; Ballerini,Viviana; Flynn,Luis; Limansky,Adriana S..
ABSTRACTA nosocomial polyclonal outbreak associated to bacteremia caused by differentBurkholderia cepacia complex (BCC) species and clones is reported. Molecular characterization identified Burkholderia stabilis, Burkholderia contaminans, and Burkholderia ambifaria among BCC isolates obtained from patients in neonatal and adult intensive care units. BCC was also isolated from an intrinsically contaminated ultrasound gel, which constituted the presumptive BCC source. Prior BCC outbreak related to contaminated ultrasound gels have been described in the setting of transrectal prostate biopsy. Outbreak caused strains and/or clones of BCC have been reported, probably because BCC are commonly found in the natural environment; most BCC species are biofilm...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Burkholderia cepacia complex; Outbreak; Bacteremia; Polyclonal.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000500543
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Polymerase Chain Reaction and blood culture for diagnosis of canine sepsis Ciência Rural
Silveira,Marcelo Marques da; Cândido,Stéfhano Luis; Santos,Karin Rinaldi dos; Maia,Maerle Oliveira; Souza,Roberto Lopes de; Sousa,Valéria Régia Franco; Almeida,Arleana do Bom Parto Ferreira de; Dutra,Valeria; Nakazato,Luciano.
ABSTRACT: Sepsis is characterized by the presence of organ dysfunction secondary to the dysregulated systemic inflammatory response associated with an infection, and has high mortality rates. Traditional diagnostic techniques based on non-microbiological isolation are time-consuming and may delay treatment. Thus, this study aimed to compare bacterial and fungal broad-range polymerase chain reaction (PCR) and blood culture for diagnosis of sepsis in dogs. Blood samples from 88 dogs with suspected sepsis were analyzed by blood culture, and PCR to detect bacterial and fungal DNA. On blood culture, 20 (22.7%) samples tested positive for bacterial isolates; however, none tested positive for fungi. Through PCR analysis, bacterial DNA was detected in 46 (52.3%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Blood culture; PCR; Bacteremia; Fungemia.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000600452
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Pressure ulcer as a reservoir of multiresistant Gram-negative bacilli: risk factors for colonization and development of bacteremia BJID
Braga,Iolanda A.; Brito,Cristiane S.; Diogo Filho,Augusto; Gontijo Filho,Paulo P.; Ribas,Rosineide M..
Abstract The purpose of this study was to identify the risk factors that predispose patients who are hospitalized with pressure ulcers (PUs) colonized by Gram-negative bacilli (GNB) to develop bacteremia. In addition, we also detected main phenotypes of resistance in infected and uninfected PUs. A prospective cohort study was conducted at the Clinical Hospital of the Federal University of Uberlândia including patients with Stage II or greater PUs, colonized or not with GNB, from August 2009 to July 2010. Infected ulcers were defined based on clinical signs and on positive evaluation of smears of wound material translated by a ratio of polymorphonuclear cells to epithelial cells ≥2:1, after Giemsa staining. A total of 60 patients with Stage II PUs were...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Pressure ulcer; Gram-negative bacilli; Colonization; Bacteremia.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000200171
Registros recuperados: 30
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